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Sailing the surfactant sea:
Dynamics of rig= id and flexible bodies in
interfaces and membranes
Alex J. Levine
Department of Chemistry and Biochemistry
University of California, Los Ang= eles
University of Color= ado, Boulder
August 2006<= /div>
P.G. Saffman and M. Delbrück, <= i>Brownian Motion in Biological Membr= anes, Proc. Nat. Acad. Sci.  <= /span>72, 3111 (1975).
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Collaborators (Theory)
<= span style=3D'font-family:"Times New Roman"'>• F.C. Mackintosh
<= span style=3D'font-family:"Times New Roman";visibility:hidden'>•=
<= span style=3D'font-family:"Times New Roman";visibility:hidden'>•=
• T.B. Liverpool
<= span style=3D'font-family:"Times New Roman";visibility:hidden'>•=
<= span style=3D'font-family:"Times New Roman";visibility:hidden'>•=
<= span style=3D'font-family:"Times New Roman"'>• M. Henle
3D"[University
Collaborators (Experiment)
•=  A.D. Dinsmore, R. McGorty
• <= /span>
•=  M. Dennin
• <= /span>
•=  V. Prasad, S. Koeh= ler,
and E. Weeks
Papers
•<= /span> A.J. Levine and F.C MacKintosh “Dynamics of viscoelastic membranes” PRE 66, 061606 (2002) = ;
• <= /span>
•<= /span> A.J. Levine, T.B. Liverpool, and F.C. MacKintosh “Mobility of extended bodies in viscous = 3;
films and monolayers” PRE 69, 021503 (2004).= 3;
• <= /span>
•<= /span> A.J. Levine, T.B. Liverpool, and F.C. MacKintosh “Dynamics of rigid and flexible extended &#= 13;
bodies in viscous films and membranes” PR= L 93, 038102 (2004).
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Hydrodynamics in membranes and on monolayers:
The importance of looking below the surface
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Mobilities of particles in a membrane
How to determine t= he particle mobilities?
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•=  Microrheology in membranes/interfaces: Both translational and rotational =
(E. Weeks) Two-particle microrheology on interfaces.
•= Dynamics of phases separation in multi-component membranes
• =
Lipid raft formation as 2d phase separat= ion.
Transmembrane  protein aggregation kinetics
•= Dynamics of rigid or semiflexible rods in membranes/interfaces
<= span style=3D'mso-special-format:bullet;position:absolute;left:-1.32%'>•=
 (J. Zasadzinski) Needle viscometry =
 (M. Dennin) Actin dynamics on a monolay= er.
=
(A.D. Dinsmore) Rod mobilities on the surface of spherical droplets <= /div>
Why consider membr= ane hydrodynamics?
------=_NextPart_01C6F3A7.6ED13450 Content-Location: file:///C:/A0BE1EAF/membrane-hydro_files/slide0051.htm Content-Transfer-Encoding: quoted-printable Content-Type: text/html; charset="windows-1252" Slide 1
Rapid respreading = of lung surfactant is important for minimizing the
work of inhalation=
Needle viscometry<= /span>
Understanding the physical properties of lung surfactant
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Content-Location: file:///C:/A0BE1EAF/membrane-hydro_files/slide0005.htm Content-Transfer-Encoding: quoted-printable Content-Type: text/html; charset="windows-1252" Slide 1
Describing the dynamics of a membrane or interface:
Boundary
 Conditions:
Displacement field
on the globally flat <= /span>
interface:
Flow of the
Newtonian
Sub/super-phase:
Velocity decays into the
infinite surrounding fluid.
No slip
Vertical Displacement =
of the interface: <= /div>
=
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